Flaminal® works in three ways to effect wound healing.
1. Keeps the wound moist through its hydrating properties;
2. Cleans the wound by breaking down the old and dying tissue and taking it out via absorption into the gel structure &
3. Kills the bacteria in the wound using its broad spectrum antibacterial enzyme system¹.
Flaminal® complies with the T.I.M.E. principle – the European Wound Management Association guidelines for chronic wound treatment.
1. Keeps the wound moist and protects wound edges.
The alginate component, with hydrating and absorbing properties, creates the optimal moist environment for the wound. In addition, alginate flakes from Flaminal® may form on the wound edge to further protect wound edges during the healing process.
2. A clean wound via continuous auto-debridement.
The alginate in Flaminal® breaks down necrotic tissue through hydration and autolysis. Flaminal® debrides the wound by absorbing the lysed necrotic tissue and the excess of wound exudate, including bacteria into the gel structure.
3. Specific broad spectrum anti-bacterial activity is provided through a patented anti-bacterial enzyme system¹.
The novel system kills bacteria, including many of the pathogens commonly found in wounds such as MRSA, VREF and multi-resistant Pseudomonas. Flaminal’s® antibacterial enzyme system has no effect on dermal and epidermal cells that are responsible for wound healing.
Flaminal’s® antibacterial properties rely on the action of two naturally occurring enzymes:
* Glucose oxidase, also found in honey &
* Lactoperoxidase, produced by mammals in tears, mucous and milk
Glucose oxidase converts water and oxygen absorbed from the wound exudate into peroxide ions. These ions are then captured by the lactoperoxidase to form free radicals that destroy the cell walls of absorbed bacteria.
As this is a selective process, only absorbed bacterial cell walls are destroyed and not the cell walls of human cells within the wound bed, such as keratinocytes and fibroblasts.
No bacterial resistance to Flaminal® has been reported.
Flaminal® is hypoallergenic and non-cytotoxic².
1. White R “Flaminal: a novel approach to wound bioburden control” Wounds UK 2006, 2(3):64-69
2. Vandenbulcke K et al “Evaluation of the Antibacterial Activity and Toxicity of 2 Hydrogels: a Pilot Study” Lower Extremity Wounds 2006 5(2): 109-114
